Sensory Neurons Link the Nervous System and Autoimmune Diabetes

نویسندگان

  • Helene Bour-Jordan
  • Jeffrey A. Bluestone
چکیده

The initial factors that trigger the autoimmune response against pancreatic islets in the nonobese diabetic (NOD) mouse are still unknown. In this issue of Cell, propose that a defect in a subset of sensory neurons innervating the pancreas plays a major role in initiating the chain of events that will lead to local inflammation, islet destruction, and autoimmune diabetes.

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عنوان ژورنال:
  • Cell

دوره 127  شماره 

صفحات  -

تاریخ انتشار 2006